No evidence of antigenic seniority in hemagglutinin specific antibody responses after adjuvanted pandemic 2009 influenza vaccination
Identifieur interne : 000062 ( Main/Exploration ); précédent : 000061; suivant : 000063No evidence of antigenic seniority in hemagglutinin specific antibody responses after adjuvanted pandemic 2009 influenza vaccination
Auteurs : Anders Madsen [Norvège] ; Linda Azimi [Norvège] ; Sarah Tete [Norvège] ; Fan Zhou [Norvège] ; Florian Krammer [États-Unis] ; Rebecca Jane Cox [Norvège] ; Ne Jul-Larsen [Norvège]Source :
- Vaccine: X [ 2590-1362 ] ; 2019.
Abstract
AS03-adjuvanted H1N1pdm09 vaccine elicited robust antibody responses. More antigenically experienced individuals had higher pre-vaccination HA stalk specific antibodies. AS03 adjuvanted H1N1pdm09 vaccine overcomes problems of antigenic seniority.
Url:
DOI: 10.1016/j.jvacx.2019.100029
PubMed: 31384744
PubMed Central: 6668305
Affiliations:
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Jebsen Centre for Influenza Vaccine Research, Department of Clinical Science, University of Bergen</wicri:regionArea><wicri:noRegion>University of Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Krammer, Florian" sort="Krammer, Florian" uniqKey="Krammer F" first="Florian" last="Krammer">Florian Krammer</name><affiliation wicri:level="2"><nlm:aff id="af015">Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Cox, Rebecca Jane" sort="Cox, Rebecca Jane" uniqKey="Cox R" first="Rebecca Jane" last="Cox">Rebecca Jane Cox</name><affiliation wicri:level="1"><nlm:aff id="af005">Influenza Centre, Department of Clinical Science, University of Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Influenza Centre, Department of Clinical Science, University of Bergen</wicri:regionArea><wicri:noRegion>University of Bergen</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="af010">K.G. 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Jebsen Centre for Influenza Vaccine Research, Department of Clinical Science, University of Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>K.G. Jebsen Centre for Influenza Vaccine Research, Department of Clinical Science, University of Bergen</wicri:regionArea><wicri:noRegion>University of Bergen</wicri:noRegion></affiliation></author></analytic><series><title level="j">Vaccine: X</title><idno type="eISSN">2590-1362</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="l0005"><list-item id="o0005"><label>•</label><p id="p0005">AS03-adjuvanted H1N1pdm09 vaccine elicited robust antibody responses.</p></list-item><list-item id="o0010"><label>•</label><p id="p0010">More antigenically experienced individuals had higher pre-vaccination HA stalk specific antibodies.</p></list-item><list-item id="o0015"><label>•</label><p id="p0015">AS03 adjuvanted H1N1pdm09 vaccine overcomes problems of antigenic seniority.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Iuliano, A D" uniqKey="Iuliano A">A.D. 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Robinson</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Norvège</li><li>États-Unis</li></country><region><li>État de New York</li></region></list><tree><country name="Norvège"><noRegion><name sortKey="Madsen, Anders" sort="Madsen, Anders" uniqKey="Madsen A" first="Anders" last="Madsen">Anders Madsen</name></noRegion><name sortKey="Azimi, Linda" sort="Azimi, Linda" uniqKey="Azimi L" first="Linda" last="Azimi">Linda Azimi</name><name sortKey="Cox, Rebecca Jane" sort="Cox, Rebecca Jane" uniqKey="Cox R" first="Rebecca Jane" last="Cox">Rebecca Jane Cox</name><name sortKey="Cox, Rebecca Jane" sort="Cox, Rebecca Jane" uniqKey="Cox R" first="Rebecca Jane" last="Cox">Rebecca Jane Cox</name><name sortKey="Cox, Rebecca Jane" sort="Cox, Rebecca Jane" uniqKey="Cox R" first="Rebecca Jane" last="Cox">Rebecca Jane Cox</name><name sortKey="Jul Larsen, Ne" sort="Jul Larsen, Ne" uniqKey="Jul Larsen " first=" Ne" last="Jul-Larsen"> Ne Jul-Larsen</name><name sortKey="Jul Larsen, Ne" sort="Jul Larsen, Ne" uniqKey="Jul Larsen " first=" Ne" last="Jul-Larsen"> Ne Jul-Larsen</name><name sortKey="Tete, Sarah" sort="Tete, Sarah" uniqKey="Tete S" first="Sarah" last="Tete">Sarah Tete</name><name sortKey="Tete, Sarah" sort="Tete, Sarah" uniqKey="Tete S" first="Sarah" last="Tete">Sarah Tete</name><name sortKey="Zhou, Fan" sort="Zhou, Fan" uniqKey="Zhou F" first="Fan" last="Zhou">Fan Zhou</name><name sortKey="Zhou, Fan" sort="Zhou, Fan" uniqKey="Zhou F" first="Fan" last="Zhou">Fan Zhou</name></country><country name="États-Unis"><region name="État de New York"><name sortKey="Krammer, Florian" sort="Krammer, Florian" uniqKey="Krammer F" first="Florian" last="Krammer">Florian Krammer</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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